Principal Investigator

Ju-Sheng Zheng

Ju-Sheng Zheng


  • Tel: +86-0571-86915303

  • Principal Investigator

    Ju-Sheng got his PhD degree in nutrition at Zhejiang University, Hangzhou, China (2009-2014). Within his PhD program, he received one year’s training in the Nutrition and Genomics Lab at Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University in the USA (2012). He was also a Marie Skłodowska-Curie Individual Fellow supported by the European Commission and a postdoctoral researcher at the MRC Epidemiology Unit, University of Cambridge, UK (2015-2018).

    Ju-Sheng joined the School of Life Sciences at Westlake University as a principal investigator and assistant professor in September 2018. He serves as associate editor for BMC Med and statistical editor for Asia Pac J Clin Nutr. He has published over 90 peer-reviewed papers in leading journals such as BMJ, Gut, Diabetes Care, PLoS Med, Microbiome, BMC Med, Am J Clin Nutr, et al.

    Current Interests

    1. Precision nutrition: using novel study design (n-of-1 clinical trial) or wearable device (such as continuous glucose monitoring) to explore individual’ personalized response to diet and nutrition in the Chinese populations. Using multi-omics technologies to unveil the mechanism behind the link between nutrition and chronic diseases with large-scale human cohort data.

    2. Computational Medicine: Use computational methods and multi-omics datasets (including nutrition biomarkers, genomics, metabolomics, microbiome and proteomics) within human cohorts to investigate the etiology of aging-related diseases or pregnancy-related outcomes, and to identify novel disease biomarkers and prioritize potential drug targets.

    Selected Publications

    (# Equal contribution, * Corresponding authors)

    1. Zheng JS. Mapping the Chinese microbiome: it's time for a united effort. Nature. 2023.

    2. Miao Z, Zeng F, Tian Y, Xiao C, Yan Y, Jiang Z,...,Chen YM*, Zheng JS*. Furan fatty acid metabolite CMPF was associated with lower risk of type 2 diabetes, but not chronic kidney disease: A longitudinal population-based cohort study. Am J Clin Nutr. 2023.

    3. Jia J#, Shuai M#, Yan W, Tang Q, Wang B, Tang W, ..., Fu Y*, Cai W*, Zheng JS*. Conserved covarying gut microbial network in preterm infants and childhood growth during the first 5 years of life: a prospective cohort study. Am J Clin Nutr. 2023.

    4. Liang X, Miao Z, Lu S, Ye M, Wang J, Zhao H, Xiao C, Shuai M, Gou W, Liang Y, Xu F, Shi M, Wu Y, Wang X, Cai F, Xu M, Fu Y, Hu W*, Zheng JS*. Integration of multiomics with precision nutrition for gestational diabetes: Study protocol for the Westlake Precision Birth Cohort. iMeta. 2023.

    5. Tian Y, Gou W, Ma Y, Shuai M, Liang X, Fu Y*, Zheng JS*. The Short-Term Variation of Human Gut Mycobiome in Response to Dietary Intervention of Different Macronutrient Distributions. Nutrients. 2023.

    6. Xu F, Yu EY, Cai X, Yue L, Jing LP, Liang X, Fu Y, Miao Z, Yang M, Shuai M, Gou W, Xiao C, Xue Z, Xie Y, Li S, Lu S, Shi M, Wang X, Hu W, Langenberg C*, Yang J*, Chen YM*, Guo T*, Zheng JS*. Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility. Nat Commun. 2023.

    7. Deng K, Xu JJ, Shen L, Zhao H, Gou W, Xu F, Fu Y, Jiang Z, Shuai M, Li BY, Hu W, Zheng JS*, Chen YM*. Comparison of fecal and blood metabolome reveals inconsistent associations of the gut microbiota with cardiometabolic diseases. Nat Commun. 2023.

    For a full list of ZhengLab's publication, pleace click Google Scholar |PubMed.